A computerized model for the self-non-self discrimination at the level of the Th (Th genesis). I. The origin of 'primer' effector Th cells
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منابع مشابه
A computerized model for the self-non-self discrimination at the level of the T(h) (Th genesis). I. The origin of 'primer' effector T(h) cells.
The ability of the immune system to respond by ridding a pathogen without debilitating the host depends upon the ability of the effector T(h) (eT(h)) to make a discrimination between 'self' and 'non-self' antigens. This ability is somatically learned and involves the sorting of the somatically generated random repertoire of initial state T(h) (iT(h)) into two classes of specificity: one, anti-s...
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ژورنال
عنوان ژورنال: International Immunology
سال: 2002
ISSN: 0953-8178,1460-2377
DOI: 10.1093/intimm/dxf078